000 Bronchopneumonia

    • What is it:
      • Bronchopneumonia refers to:
        • A radiological and pathological finding
        • characterized by
          • patchy areas of
            • inflammation or
            • infection within the
            • lung parenchyma,
        • centered around the bronchi and bronchioles, and extending into adjacent alveoli.
      • It reflects:
        • A localized infectious or inflammatory process, most commonly caused by bacterial pathogens.
      • Non-specific term:
        • While typically associated with bacterial infection, bronchopneumonia may also describe:
          • Non-infectious inflammatory processes, or
          • Aspiration-related lung injury.
      • Coexistence with Atelectasis:
        • Bronchopneumonia can coexist with atelectasis due to:
          • Obstruction of airways by inflammatory exudates or mucus plugs, leading to lung segment collapse.
    • Etymology:
      • Derived from the Greek words bronchos (windpipe) and pneumon (lung), referring to lung infection involving the bronchi and surrounding parenchyma.
    • AKA:
      • Bronchial pneumonia, Patchy pneumonia.
    • How does it appear on each relevant imaging modality:
      • Chest X-ray:
        • Patchy opacities in a peribronchial distribution, often bilateral and asymmetric.
        • Poorly defined margins blending into surrounding lung tissue.
        • Areas of atelectasis may appear as linear opacities or volume loss adjacent to infected regions.
      • Chest CT:
        • Parts:
          • Multifocal areas of consolidation and ground-glass opacities, centered around the bronchi and bronchioles.
        • Size:
          • Patchy, typically affecting segments or subsegments.
        • Shape:
          • Ill-defined, irregular opacities.
        • Position:
          • Peribronchial and peribronchiolar, often involving dependent lung regions.
          • Coexisting atelectasis: Subsegmental or segmental collapse near bronchopneumonic areas.
        • Character:
          • Mixed alveolar and interstitial patterns.
          • Air bronchograms may be present within consolidated areas.
        • Time:
          • Rapid onset with infectious etiology; resolves or evolves with treatment.
      • Ultrasound:
        • Subpleural consolidations may be visible in accessible areas.
      • MRI:
        • Rarely used; may highlight peribronchial inflammation and associated consolidation.
    • These findings reflect:
      • Infectious causes:
        • Bacterial pneumonia:
          • Common pathogens: Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa.
        • Viral pneumonia:
          • Secondary bacterial infection complicating influenza or RSV.
      • Non-infectious causes:
        • Aspiration pneumonia.
        • Organizing pneumonia (secondary to infection or inflammation).
      • Atelectasis coexistence:
        • Associated with airway obstruction by mucus plugs or debris in bronchopneumonia.
    • Differential diagnosis:
      • Infectious mimics:
        • Viral pneumonias without consolidation.
        • Tuberculosis with patchy opacities.
      • Non-infectious mimics:
        • Aspiration-related pneumonitis.
        • Organizing pneumonia or ARDS.
      • Malignant processes:
        • Bronchoalveolar carcinoma with patchy consolidation.
    • Recommendations:
      • Correlate imaging findings with clinical history, including symptoms (e.g., fever, cough) and laboratory markers (e.g., leukocytosis, sputum cultures).
      • Use Chest CT for detailed characterization if findings are atypical or diagnostic uncertainty persists.
      • Assess for coexisting atelectasis, which may complicate ventilation and recovery.
      • Consider bronchoscopy if mucus plugs or airway obstruction are suspected as contributing to atelectasis.
    • Key points and pearls:
      • Patchy distribution distinguishes bronchopneumonia from lobar pneumonia.
      • Bronchopneumonia is more common in the elderly, immunocompromised, or individuals with aspiration risks.
      • Atelectasis coexisting with bronchopneumonia can result in volume loss and hypoxemia, requiring specific management.
      • Persistent findings may indicate organizing pneumonia or malignancy and warrant further evaluation.