131Lu Active TB with Transbronchial Spread

28 y.o. male who recently underwent biopsy of a non-healing ulcer in the perianal region Pathology showed granulomatous inflammation and cultures have now isolated M. Tuberculsosis and referred to TB clinic.

3 months prior

Cough which started for about 8 months  which lasted approx a few weeks; non productive.

Cough resolved and then about 2 months later the cough recurred and was productive, which initially appeared to improve but now says over the past 2 months he has had a persistent cough, worse in the AM.

Sputum is brownish and thick in the AM and then later turns yellow. No blood

Active TB with Transbronchial Spread
Ashley Davidoff MD
TheCommonVein.net
Active TB with Transbronchial Spread
Ashley Davidoff MD
TheCommonVein.net
  • Chest x-ray shows bilateral patchy opacities with multiple lesions that appear cavitary, consistent with pulmonary TB
  • extrapulmonary disease involving the perianal area.
  • Sigmoidoscopy  did not reveal any evidence of fistula.
  • Given perianal ulcer, query extension from the rectum vs genitourinary tract despite lack of symptoms.
  • HIV negative.
  • 4+ smear positive and isolated M. TB

2 Months Later

1 Month LAterActive TB with Transbronchial Spread
Ashley Davidoff MD
TheCommonVein.net

 

1 Month Later

CAvitation Atelectasis Bronchovascular Involvement

Large cavitary lesion in the left upper lobe and a smaller cavitary lesionin the right upper lobe concerning for granulomatous
disease such as tuberculosis.

Additional numerous patchy nodular opacities in bilateral lungs as
described above with tree-in-bud appearance representing endobronchialspread .