179 Lu Chronic Eosinophilic Pneumonia

60 y.o. female with a history of GERD, and HTN and
admission 3 years prior
- for chronic cough,
- fevers,
- dyspnea, and
- fatigue
  - biopsy proven
  - subacute and
  - chronic
  - organizing eosinophilic PNA
  - progressive phase of subacute to chronic eosinophilic pneumonia, including
    - interstitial fibrosis,
    - intraalveolar fibrin deposits with
    - eosinophils and
    - lymphohistiocytoses and
    - fibroblastic proliferation foci.
  - ORGANIZING PNEUMONIA SHOWING SUBACUTE AND CHRONIC PHASES, FIBRINOUS AIRSPACE EXODUATES WITH ADMIXED EOSINOPHILS AND HISTIOCYTES.
    THE DISTRIBUTION IS MULTIFOCAL AND PATCHY.
    NO EVIDENCE OF VASCULITIS OR GRANULOMA SEEN.
- started on prednisone
- started on mepolizumab 1 year later and
- weaned off prednisone 2 years ago
- with improvement of symptoms and
- CXR now presenting for a follow up.