188Lu Squamous Cell Carcinoma with SVC Syndrome

  • 55-year-old male heavy smoker with history of
    • squamous cell carcinoma of the right lung with
    • invasion of the right mainstem bronchus and
    • encasement of the right pulmonary artery and
    • SVC
    • Requiring stents
    • Stage IIIC cT1bN3M0
    • is status post chemotherapy and
    • radiation therapy

Normal  CXR 7 years ago

Normal  CXR 7 years ago
55 year old male with central squamous cell carcinoma of the lung presents 7 years ago showing a normal CXR 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-001

 

4 years Later Presents with a Cough

55 year old male with central squamous cell carcinoma of the lung presents 4 years later with a cough  CXR shows an enlarged azygous region 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-002

Primary Lesion in the Right Main Stem Bronchus

55 year old male with central squamous cell carcinoma of the lung presents 3 years later with a cough CT shows a large mediastinal mass in the azygous region causing compression on the SVC and a primary lesion in the right mainstem bronchus
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-006

CT Shows a Large Central Mass Likely a Nodal Metasasis with Invasion into Right Upper Lobe Pulmonary Artery

55 year old male with central squamous cell carcinoma of the lung presents 3 years later with a cough CT shows a large mediastinal mass in the azygous region with compression and encasement of the right upper lobe pulmonary artery
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-003

PET scan

 

PET scan shows an endobronchial mass within the right mainstem bronchus with intense FDG uptake, corresponding to biopsy-proven squamous cell carcinoma assocciated with a large positive mediastinal node
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-007
PET scan shows an endobronchial mass within the right mainstem bronchus with intense FDG uptake, corresponding to biopsy-proven squamous cell carcinoma assocciated with a large positive mediastinal node
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-007b

 

The dominant right lower paratracheal mass encases the right main
pulmonary artery demonstrates intense FDG uptake, corresponding withnodal metastasis. Right upper paratracheal and prevascular nodalconglomerates with mild and moderate FDG uptake also likely representnodal metastatic disease. Uptake in bilateral infraclavicular lymph nodes (left greater than right) most worrisome for metastatic disease.

1 Month Later with Progressive Symptoms

55 year old male with central squamous cell carcinoma of the lung presents 1 month later with progressive symptoms  CT shows a large mediastinal node in the azygous region causing compression and possible invasion of  the SVC 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-008
55 year old male with central squamous cell carcinoma of the lung presents 1 month later with progressive symptoms  CT shows a large mediastinal mass in the azygous region causing compression and possible invasion of  the SVC 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-008b

 

Progressive Subtotal Occlusion of the Right Main Stem Bronchus 

55 year old male with central squamous cell carcinoma of the lung presents 1 month later with progressive symptoms  CT shows a large mediastinal mass in the azygous region and a growing lesion in the right main stem bronchus with almost  subtotal occlusion .
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-009

 

 

Progressive Encasement  of the Right Upper Lobe Pulmonary Artery

55 year old male with central squamous cell carcinoma of the lung presents 1 month later with progressive symptoms  CT shows a large mediastinal mass in the azygous region causing progressive narrowing  of the right upper lobe pulmonary artery
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-009

 

Stents in SVC and Brachiocephalic Vein and XRT and Chemotherapy Initiated

Resolution of Primary Mass

55 year old male with central squamous cell carcinoma of the lung presents for follow up following stent placement in the SVC and innominate vein, XRT and chemotherapy showing resolution of the primary mass shrinkage of the mediastinal node and patency of the stents 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-011

Functioning  Stents

55 year old male with central squamous cell carcinoma of the lung presents for follow up following stent placement in the SVC and innominate vein, XRT and chemotherapy showing resolution of the primary mass shrinkage of the mediastinal node and patency of the stents 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-010
55 year old male with central squamous cell carcinoma of the lung presents for follow up following stent placement in the SVC and innominate vein, XRT and chemotherapy showing resolution of the primary mass shrinkage of the mediastinal node and patency of the stents 
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-013

 

Improved Patency of the Right Upper Lobe Artery


55 year old male with central squamous cell carcinoma of the lung presents for follow up following stent placement in the SVC and innominate vein, XRT and chemotherapy showing resolution of the primary mass shrinkage of the mediastinal node improved patency of the right upper lobe pulmonary artery
Ashley Davidoff MD TheCommonVein.net squamous cell carcinoma 55-012