252Lu Desquamative Interstitial Pneumonia

  • 51  y.o. female with PMH of asthma/COPD, PAH on
  • DIP (dxed by lung biopsy in 1999),
  • Chest CT
    • Stable reticulations and
    • ground glass opacities at the periphery of the
      lung bases,
    • component of honeycombing versus bronchiolectasis.
    • air trapping in the lower lung field suggesting small
      airway disease
    • Background severe centrilobular emphysema
      Postsurgical changes from right upper lobe wedge resection with severe emphysematous changes.

CXR Desquamative Interstitial Pneumonia DIP and Emphysema

CXR Desquamative Interstitial Pneumonia DIP and Emphysema
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Frontal chest Xray shows diffuse bilateral interstitial disease characterised by coarsening of the lung markings and an enlarged main pulmonary artery (MPA). Path confirmed diagnosis of DIP.
Ashley Davidoff MD TheCommonVein.net 252Lu 135957
CXR Desquamative Interstitial Pneumonia DIP and Emphysema
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Lateral chest Xray shows flattening of the diaphragms indicating hyperinflation and diffuse bilateral interstitial disease characterised by coarsening of the lung markings and an enlarged main pulmonary artery (MPA) The transverse fissure is thickened. Path confirmed diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135958
CXR Desquamative Interstitial Pneumonia DIP and Emphysema
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Lateral chest Xray shows flattening of the diaphragms indicating hyperinflation and diffuse bilateral interstitial disease characterised by coarsening of the lung markings and an enlarged main pulmonary artery (MPA) The transverse fissure is thickened. Path confirmed diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135958

Emphysema  and Bronchial Wall Thickening Upper Lung Fields

CT Desquamative Interstitial Pneumonia Emphysema  and Bronchial Wall Thickening Upper Lung Fields
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the upper lung fields shows extensive changes of centrilobular emphysema associated with peribronchial thickening noted in the right upper lobe Path confirmed diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135961c

Enlarged Group of Secondary Lobules

CT Desquamative Interstitial Pneumonia Emphysema Upper Lung Fields Enlarged Group of Secondary Lobules
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the upper lung fields shows extensive changes of centrilobular emphysema and an expanded group of secondary lobules noted in the right upper lobe Path confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135963c

Fissural Irregularity and Thickened Septa

CT Desquamative Interstitial Pneumonia Emphysema Upper Lung Fields Fissural Irregularity and Thickened Septa
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the upper lung fields at the level of the carina shows extensive changes of centrilobular emphysema and ground glasses changes in the anterior segments – right more prominent than the left. In addition there is irregularity of the right major fissure (lower panel) seemingly as a result of the enlarged secondary lobule, and stress on the fissure by the interlobular septa. Path confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135965c

Upper Lung Fields Transforming from
Emphysematous Changes to Ground Glass

CT Desquamative Interstitial Pneumonia Emphysema Upper Lung Fields Transforming from Emphysematous Changes to Ground Glass
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the upper lung fields at the level of the carina shows progression from extensive centrilobular changes to ground glass changes in the left anterior segment, and diffuse ground glass changes in the lower lobes. In addition, there is irregularity of the right major fissure seemingly as a result of the enlarged secondary lobule, and stress on the fissure by the interlobular septa. Path confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135966

Emphysema Upper Lung Fields Transforming from Emphysematous Changes to Ground Glass
Thickened Irregular Fissure

CT Desquamative Interstitial Pneumonia Emphysema Upper Lung Fields Transforming from Emphysematous Changes to Ground Glass Thickened Irregular Fissure
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the upper lung fields at the level of the carina shows progression from extensive centrilobular changes to ground glass changes in the left anterior segment, and diffuse ground glass changes in the lower lobes. In addition, there is irregularity of the right major fissure (lower panel) seemingly as a result of the enlarged secondary lobule, and stress on the fissure by the interlobular septa. Path confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135966c

Patchy Ground Glass Changes

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the lower lung fields shows patchy ground glass changes in the middle lobe inferior ligula and lower lobes and some regions of mosaicism. There is mild subsegmental airway thickening. Early honeycomb changes are suggested in the right lower lobe. Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135968

Patchy Ground Glass Changes

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the lower lung fields shows patchy ground glass changes in the middle lobe inferior ligula and lower lobes and some regions of mosaicism. There is mild subsegmental airway thickening. Early honeycomb changes are suggested in the right lower lobe. Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135969

Patchy Ground Glass Changes

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the lower lung fields shows patchy ground glass changes in the middle lobe inferior ligula and lower lobes and some regions of mosaicism. Focal regions of interlobular septal thickening are noted left lower lobe (lower panel). Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135969c

Patchy Ground Glass Changes and Bronchiolectasis

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes and Bronchiolectasis
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the lower lung fields shows patchy ground glass changes in the middle lobe inferior ligula and lower lobes and some regions of mosaicism. Focal regions of interlobular septal thickening are noted left lower lobe and evidence of thick walled bronchiolectasis in the right lower lobe (lower panel). Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135972c

Patchy Ground Glass Changes, Bronchiolectasis, and Mosaicism

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes, Bronchiolectasis, and Mosaicism
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the lower lung fields shows patchy ground glass changes in the middle lobe inferior ligula and lower lobes and some regions of mosaicism. There is evidence of thick-walled bronchiolectasis in the right lower lobe Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135976

,Bronchiolectasis Mosaicism and the Secondary Lobul

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes,  Bronchiolectasis Mosaicism and the Secondary Lobule
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the right posterior recess shows patchy ground glass changes with some regions of mosaicism. The bronchovascular bundle subtending 2 secondary lobules is highlighted in the lower panel. The centrilobular arteriole and ectatic bronchiole are magnified
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135981c

Emphysema Upper Lung Fields
Patchy Ground Glass Changes Lower Lung Fields

CT Desquamative Interstitial Pneumonia (DIP) Emphysema Upper Lung Fields Patchy Ground Glass Changes Lower Lung Fields
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Coronal CT through the mid lung shows upper lobe centrilobular emphysematous disease and patchy ground glass changes in the lower lobes
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135990

Emphysema Upper Lung Fields
Patchy Ground Glass Changes Lower Lung Fields

CT Desquamative Interstitial Pneumonia (DIP) Emphysema Upper Lung Fields Patchy Ground Glass Changes Lower Lung Fields
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Coronal CT through the posterior lungs shows upper lobe centrilobular emphysematous disease and patchy ground glass changes in the lower lobes with mosaicism.
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135993

Diffuse Ground Glass Changes Lower Lung Fields and
Interlobular Septal Thickening (Crazy Paving)

CT Desquamative Interstitial Pneumonia (DIP) Diffuse Ground Glass Changes Lower Lung Fields and Interlobular Septal Thickening (Crazy Paving)
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Coronal CT through the posterior lungs shows diffuse ground glass changes in the lower lobes with interlobular septal thickening
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135997

Emphysema Right Upper Lung Field-
Patchy Ground Glass Changes Lower Lung Field

CT Desquamative Interstitial Pneumonia (DIP) Emphysema Right Upper Lung Field- Patchy Ground Glass Changes Lower Lung Field
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Sagittal CT through the lateral right mid lung shows upper lobe posterior and superior segmental centrilobular emphysematous disease and ground glass changes in the anterior segment of the upper lobe and right lower lobe
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135998

Emphysema Right Upper Lung Field-
Patchy Ground Glass Changes Lower Lung Field

CT Desquamative Interstitial Pneumonia (DIP) Emphysema Right Upper Lung Field- Patchy Ground Glass Changes Lower Lung Field
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Sagittal CT through the medial right mid lung shows upper lobe centrilobular emphysematous disease and patchy ground glass changes in the middle and right lower lobe There is thickening and irregularity of the minor fissure
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135999

Emphysema Left Upper Lung Field-
Patchy Ground Glass Changes Lower Lung Field
Thickened Septa

CT Desquamative Interstitial Pneumonia (DIP) Emphysema Left Upper Lung Field- Patchy Ground Glass Changes Lower Lung Field Thickened Septa
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Sagittal CT through the medial left lung shows upper lobe centrilobular emphysematous disease with enlarged secondary lobules, and patchy ground glass changes in the lingula and left lower lobe There is smooth thickening of the interlobular septa posteriorly
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 136000

Emphysema Left Upper Lung Field- Ground Glass Changes Lower Lung Field with Crazy Paving Pattern

CT Desquamative Interstitial Pneumonia (DIP) Emphysema Left Upper Lung Field- Ground Glass Changes Lower Lung Field with Crazy Paving Pattern
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Sagittal CT through the left lung shows upper lobe centrilobular emphysematous disease, and ground glass changes in the left lower lobe. There is smooth thickening of the interlobular septa posteriorly and a crazy paving pattern
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 136001

Patchy Ground Glass Changes and Mosaicism and Air Trapping – Inspiration Expiration Views

CT Desquamative Interstitial Pneumonia (DIP) Patchy Ground Glass Changes and Mosaicism and Air Trapping – Inspiration Expiration Views
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT through the right posterior recesses at end inspiration (upper panel) and end expiration (lower panel) confirms the presence of air trapping indicating the presence of mild small airway disease
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135987

 

Persistence of Interstitial Changes on Prone Imaging

CT Desquamative Interstitial Pneumonia (DIP) Persistence of Interstitial Changes on Prone Imaging
51-year-old female smoker with a history of COPD asthma and pulmonary hypertension presents with progressive dyspnea. Axial CT in prone position through the right posterior recesses confirms the presence of persistent interstitial lung disease
Pathology confirmed a diagnosis of DIP
Ashley Davidoff MD TheCommonVein.net 252Lu 135988

Enlarged Main Pulmonary Artery and Pulmonary Hypertension

Enlarged Main Pulmonary Artery and Pulmonary Hypertension
The main pulmonary artery is enlarged and measures 3.3cms indicating pulmonary hypertension
Ashley Davidoff MD TheCommonVein.net 252Lu 135986