60year old female cigarette smoker with COPD presents with dyspnea and new lung nodules on CXR

CT shows a mixture of thick walled cysts, nodules and cavitating nodules which reflects an evolving process of Langehans histiocytosis disease in the lungs

Thick walled cyst

Nodules and evidence of centrilobular emphysema and paraseptal emphysema

 

Cavitating Spiculated Nodule

10 Years Ago

By this time she had had surgical biopsy in the LUL and LLL and the nodules were improving

9 Years ago

5 Years ago

She developed a new spiculated nodule in the RUL

Proved to be malignant – – large cell carcinoma

4 Years ago

Shows post resection of the RUL nodule and soft tissue changes in the scar in the LUL

 

LUL lesion resected showing an adenocarcinoma

Current

Emphysema s/p bilateral adenocarcinoma

References and Links

• TCV

  • • Langerhans Cell Histiocytosis Introduction
      • Atlas
      • 015Lu Langerhans vs Inhalational Drug Cystic Disease 27M
      • 016Lu Langerhans Histiocytosis 53F
      • 062Lu Langerhans Histiocytosis
      • 80Lu Langerhans  Histiocytosis with Adenocarcinoma
      • 114Lu Pulmonary Langerhans Histiocytosis (PLHC)
      • 162Lu Pulmonary Langerhans Cell Histiocytosis and Treated TB