• critical
  reference point when assessing the posterior mediastinum and
• identifying surrounding structures.

• drains blood from the thoracic wall and upper lumbar regions into the superior vena cava, while

• anterior to the aorta and posterior to the
  trachea.

1. Chest X-Ray (CXR):
   • Appears as a thin vertical line on the right side of the mediastinum, extending downward from the azygos arch to the diaphragm.
   • Normal Appearance:
     • Smooth and curvilinear.
   • Abnormalities:
     • Deviation, widening, or irregularity suggests pathological processes affecting the mediastinum, esophagus, or adjacent lung.
2. CT Imaging:
   • Clearly visualizes the structures forming the line, including:
     • The azygos vein, esophagus, and mediastinal fat.
     • The interface between the right lung and mediastinal structures.
   • Normal Line:
     • A sharp, well-defined interface on axial cuts.
   • Abnormal Line:
     • Bowing, irregularity, or distortion due to mass effect, esophageal dilation, or other pathologies.

Common Causes of Abnormalities

1. Esophageal Disorders:
   • Esophageal Dilation:
     • Achalasia, esophageal carcinoma, or strictures can displace or distort the azygo-esophageal line.
   • Hiatal Hernia:
     • Can cause a focal bulge in the lower portion of the line.
2. Mediastinal Masses:
   • Lymphadenopathy:
     • From malignancies (e.g., lymphoma, lung cancer) or infections (e.g., tuberculosis).
   • Mediastinal Tumors:
     • Neurogenic tumors or esophageal tumors can cause deviation or widening.
3. Azygos Vein Enlargement:
   • Azygos Continuation of the IVC:
     • Congenital anomaly causing a widened azygo-esophageal line.
   • Venous Congestion:
     • Secondary to right heart failure or superior vena cava syndrome.
4. Pleural Disease:
   • Pleural Effusion:
     • May obscure the lower portion of the azygo-esophageal line.
   • Right Lower Lobe Atelectasis:
     • Causes a shift toward the collapsed lung, narrowing the line.
5. Other Causes:
   • Vertebral Abnormalities:
     • Scoliosis or kyphosis can distort the line.
   • Subcarinal Pathology:
     • Enlarged lymph nodes or masses in the subcarinal region.

Clinical Relevance

The azygo-esophageal line is a subtle but important feature in chest imaging. Changes in its appearance can provide clues to underlying mediastinal or esophageal diseases, prompting further diagnostic workup (e.g., CT, endoscopy).