Diagram Alveolar Proteinosis Position of DiseasePerihilar distributionAshley Davidoff MD TheCommonvein.net lungs-0770 Alveolar ProteinosisAccumulation of proteinaceous material in the alveoli, impairing gas exchange and leading to respiratory failure. Extensive thickening of interlobular septa leading to crazy paving appearance. Half filled alveoli lead to ground glass appearanceAshley Davidoff TheCommonVein.net lungs-0738b