Faces of Cystic Lung Disease

Parts
Size

Variably Sized
Chronic Pulmonary Langerhans Cell Histiocytosis (PLCH)
CT Sagittal Plane  Multiple Thin Walled Cysts Upper Lobe
54 year old smoker presents with a chronic cough.   CT in the sagittal plane shows multiple thin walled cysts of varying size with upper lung predominance.  
Findings are consistent with chronic pulmonary Langerhans cell histiocytosis (PLCH)
Ashley Davidoff MD TheCommonvein.net 279Lu 136475


Shape

In a Wedge Shape Accumulation
Septic Emboli

76year old female presents with dyspnea  sepsis and bacteremia, 
Axial CT  reveals a large wedge shaped thick walled complex multicystic lesion associated with a feeding bronchovascular bundle (feeding vessel sign) in the right apex consistent with a cavitating infarction (cavitating Hampton’s hump).  In addition there is a second smaller unilocular thick-walled cyst with a small air fluid level suggesting infection.  There are pleural effusions.   Echo showed tricuspid valve vegetations.  Diagnosis is consistent with cavitating septic emboli
Ashley Davidoff TheCommonVein.net 33012 307Lu
76year old female presents with dyspnea  sepsis and bacteremia, 
Axial CT  reveals a large wedge shaped thick walled complex multicystic lesion ( bordered by orange lines in b) associated with a feeding bronchovascular bundle (red ring b -feeding vessel sign) in the right apex consistent with a cavitating infarction (cavitating Hampton’s hump).  In addition there is a second smaller unilocular thick-walled cyst with a small air fluid level (yellow arrow, a) suggesting additional purulence in this clinical context.  There are bilateral pleural effusions.   Echo showed tricuspid valve vegetations.  Diagnosis is consistent with cavitating septic emboli with pulmonary infarction.
Ashley Davidoff TheCommonVein.net 33012 307Lu
76year old female presents with dyspnea  sepsis and bacteremia
Axial CT  reveals a thick walled wedge shaped bilocular cystic  lesion in a region of subsegmental consolidation associated with a feeding bronchovascular bundle (feeding vessel sign).  There are large bilateral pleural effusions associated with compressive atelectasis.   Echo showed tricuspid valve vegetations.  Diagnosis is consistent with cavitating septic emboli
Ashley Davidoff TheCommonVein.net 33015cL 307Lu


Position

Upper Lung Zones
Chronic Pulmonary Langerhans Cell Histiocytosis (PLCH)
CT Coronal Multiple Thin Walled Cysts Upper Lobe
54 year old smoker presents with a chronic cough.   CT in the coronal plane shows multiple thin walled cysts of varying size with upper lung predominance
Findings are consistent with chronic pulmonary Langerhans cell histiocytosis (PLCH)
Ashley Davidoff MD TheCommonvein.net 279Lu 136470c
CT Coronal Multiple Thin Walled Cysts Upper Lobe
54 year old smoker presents with a chronic cough.   CT in the coronal plane shows multiple thin walled cysts of varying size with upper lung predominance.  The cysts appear to be aligned with a normal sized subsegmental airway with minimal wall thickening (ringed in white lower image) 
Findings are consistent with chronic pulmonary Langerhans cell histiocytosis (PLCH)
Ashley Davidoff MD TheCommonvein.net 279Lu 136472cL
CT Sagittal Plane  Multiple Thin Walled Cysts Upper Lobe
54 year old smoker presents with a chronic cough.   CT in the sagittal plane shows multiple thin walled cysts of varying size with upper lung predominance.  
Findings are consistent with chronic pulmonary Langerhans cell histiocytosis (PLCH)
Ashley Davidoff MD TheCommonvein.net 279Lu 136475

Character

Thick Walled Cavitating Septic Emboli

76year old female presents with dyspnea  sepsis and bacteremia, 
Axial CT  reveals a large wedge shaped thick walled complex multicystic lesion ( bordered by orange lines in b) associated with a feeding bronchovascular bundle (red ring b -feeding vessel sign) in the right apex consistent with a cavitating infarction (cavitating Hampton’s hump).  In addition there is a second smaller unilocular thick-walled cyst with a small air fluid level (yellow arrow, a) suggesting additional purulence in this clinical context.  There are bilateral pleural effusions.   Echo showed tricuspid valve vegetations.  Diagnosis is consistent with cavitating septic emboli with pulmonary infarction.
Ashley Davidoff TheCommonVein.net 33012 307Lu


Time Associated Findings

Infection

Inflammation

Smoking Related

CT Axial Multiple Thin Walled Cysts Upper Lobe
54 year old smoker presents with a chronic cough.   CT in the axial plane plane shows multiple thin walled cysts of varying size with upper lung predominance.  The cysts appear to be aligned with a normal sized subsegmental airway with minimal wall thickening (lower image) 
Findings are consistent with chronic pulmonary Langerhans cell histiocytosis (PLCH)
Ashley Davidoff MD TheCommonvein.net 279Lu 136478c

Malignancy

CT Chest – Cavitating Metastatic Trophoblastic Tumor

CT Chest – Cavitating Metastatic Trophoblastic Tumor
28year old female presents with vaginal bleeding for 3 days s/p ablation of a vascular molar pregnancy.  CT of the chest shows multiple cystic lesions in the lungs bilaterally with slightly thickened walls.  Wedge biopsy confirmed a diagnosis of  placental site trophoblastic tumor
Ashley Davidoff MD TheCommonVein.net
280Lu 136464.

Thick Walled Cavitating Squamous Cell Carcinoma

CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Coronal and sagittal CT reconstructions show a cavitating mass in the superior segment of the right lower lobe (upper images) correlated with axial images (lower panel)
Ashley Davidoff MD TheCommonVein.net 176Lu 136737

 

Mechanical

Atelectasis

Trauma

Metabolic

Circulatory-

Hemorrhage

Immune Infiltrative Idiopathic Iatrogenic 

Inherited

LAM and LYMPHANGIOLEIOMYOMAS in the ABDOMEN
38-year-old patient with progressive dyspnea and cough
CXR (scout for CT) shows hyperinflated lungs with increased lung volumes with bilateral and extensive thin-walled cysts surrounded by very little normal lung parenchyma. The cysts are round and thin-walled except for air filled large irregular pocket in the right apex (image 27628/29) . Some of the cysts do not have walls at all and others have an irregular configuration.
In the abdomen multiple low density lymphangioleiomyomas are present that are due to lymphatic obstruction.
Ashley Davidoff MD TheCommonvein.net
LAM and LYMPHANGIOLEIOMYOMAS in the ABDOMEN
38-year-old patient with progressive dyspnea and cough
CXR (scout for CT) shows hyperinflated lungs with increased lung volumes with bilateral and extensive thin-walled cysts surrounded by very little normal lung parenchyma. The cysts are round and thin-walled except for air filled large irregular pocket in the right apex (image 27628/29) . Some of the cysts do not have walls at all and others have an irregular configuration.
In the abdomen multiple low density lymphangioleiomyomas are present that are due to lymphatic obstruction.
Ashley Davidoff MD

Links and References

Cystic Lung Disease Brent Little  Video