Faces of ILD Interstitial Inflammation and Thickening Epicenter Interstitial changes (red parts of alveoli ) representing either infiltration into the interstitium or inflammatory changes in the interalveolar interstitiumAshley Davidoff TheCommonVein.net lungs-0736a01 Intralobular, interstial – interalveolar fibrosis (white) between the alveoliAshley Davidoff TheCommonVein.netlungs-0738b Honeycomb LungIn patients with interstitial lung disease, the inflammatory process and interstitial fibrotic disease progresses and the walls between the alveoli are destroyed causing large subpleural, variably sized, subpleural, thick walled, stacked, cystic spaces . The appearance is reminiscent of a honeycomb and indicates end stage fibrosisAshley Davidoff MD thecommonvein.net lungs-0738bh Inflammation Follicular Bronchiolitis (Bronchiolitis Obliterans) CXR Constrictive Bronchiolitis aka Bronchiolitis Obliterans70-year-old female former smoker with long standing history of RA presents with chronic dyspnea. Frontal view of the chest reveals a coarsened nodular interstitial pattern with magnified views showing the micronodularity in the lower panels.Ashley Davidoff MD TheCommonVein.net 132Lu 136650c01 CT Follicular Bronchiolitis, (aka Bronchiolitis Obliterans), Centrilobular Nodules, Air Trapping, Ground Glass Opacities (GGO) in Upper Lobes70-year-old female former smoker with long standing history of RA presents with chronic dyspnea.Axial CT of the chest at the level of the aortic arch reveals centrilobular nodules (b, white arrowheads) , ground-glass opacities, and mosaic attenuation (b, white rings) likely due to air trapping in this context, and bronchial wall thickening (b, c teal rings). There is some irregular thickening of the interlobular septa. In the context of a patient with rheumatoid arthritis a diagnosis of follicular bronchiolitis is likely. However radiologically fibrotic hypersensitivity pneumonitis (HP) is included in the differential diagnosisAshley Davidoff MD TheCommonVein.net 132Lu 136652cL CT Follicular Bronchiolitis, (aka Bronchiolitis Obliterans), Centrilobular Nodules, Air Trapping, Ground Glass Opacities (GGO) in Lower Lobes70-year-old female former smoker with long standing history of RA presents with chronic dyspnea.Axial CT of the chest at the level of the lower lung fields reveals centrilobular nodules (b white arrowheads), ground-glass opacities, and mosaic attenuation (b, white rings) likely due to air trapping in this context.In the context of a patient with rheumatoid arthritis a diagnosis of follicular bronchiolitis is likely. However radiologically fibrotic hypersensitivity pneumonitis (HP) is included in the differential diagnosisAshley Davidoff MD TheCommonVein.net 132Lu 136657cL CT Follicular Bronchiolitis, (aka Bronchiolitis Obliterans), Centrilobular Nodules, Air Trapping, Ground Glass Opacities (GGO)70-year-old female former smoker with long standing history of RA presents with chronic dyspnea.CT in the coronal plane of the chest at the level of the spine reveals bilateral diffuse changes in the lungs characterized by centrilobular nodules, ground-glass opacities, mosaic attenuation (likely due to air trapping in this context) and irregular thickening of the interlobular septa.In the context of a patient with rheumatoid arthritis a diagnosis of follicular bronchiolitis is likely. However radiologically fibrotic hypersensitivity pneumonitis (HP) is included in the differential diagnosisAshley Davidoff MD TheCommonVein.net 132Lu 136664 Bronchovascular Epicenter Pneumonia and ILD Coronal CT – Acute Aspiration Pneumonia on Chronic Interstitial Lung Disease55-year-old female with shortness of breath. CT (above) is from 4 years prior and shows an interstitial process characterized by ground glass, reticular change, and bronchiectasis. The patient presents 4 years later with fever and white count and the CT (below) shows a pneumonic process in a background of ac chronic interstitial process with cystic air spaces ns bronchiectasis, and architectural distortion. Aspiration pneumonia was considered most likelyAshley Davidoff MD TheCommonVein.net 135537 Axial CT – Acute Aspiration Pneumonia on Chronic Interstitial Lung Disease55-year-old female with shortness of breath. CT (above) is from 4 years prior and shows an interstitial process characterized by ground glass and reticular change. The patient presents 4 years later with fever and white count and the CT (below) shows a pneumonic process in a background of ac chronic interstitial process with cystic air spaces and architectural distortion. Aspiration pneumonia was considered most likelyAshley Davidoff MD TheCommonVein.net 135536 Links and References 1 Hour Video of Unknown Cases 5 star