IF Pleural Effusion Loculated Human Herpes Virus 8 and primary Effusion Lymphoma (PEL)CXR of 71-year-old male shows a complex and loculated effusion on the right and a retrocardiac infiltrate on the left, The patient has known human herpes virus which has a known association with pleural lymphoma. An entity called primary effusion lymphoma (PEL) is a rapidly progressing non-Hodgkin’s B-cell lymphoma that develops in body cavitiesAshley Davidoff MD TheCommonVein.net 135683