Upper Lung Zones and Silicosis

Upper lung field distribution
Ashley Davidoff MD TheCommonvein.net lungs-0774
Silicosis
CXR (PA view) shows interstitial reticulonodular and coalescing opacities in the lungs bilaterally consistent with a diagnosis of classic complicated silicosis. Differential diagnosis includes coal worker’s pneumoconiosis and talcosis.
Case courtesy of Dr Ian Bickle, Radiopaedia.org, rID: 33227
Silicosis with Massive Pulmonary Fibrosis
Coronal CT at the level of bronchi shows soft-tissue masses with irregular borders and significant bullous disease in bilateral lungs consistent with a diagnosis of classic complicated silicosis. Differential diagnosis includes coal worker’s pneumoconiosis and talcosis.
Case courtesy of Dr Michael P Hartung, Radiopaedia.org, rID: 71691
  • The upper lung zones are particularly vulnerable to silica dust because they have a
    • larger surface area and
    • better ventilation
      • more particles are likely to enter the upper lung zones and become
      • trapped in the alveoli,
    • larger lymphatic drainage in the upper lung zones
      • allows silica particles to more easily enter the
      • lymphatic system and
      • spread to lymph node enlargement and
      • induce autoimmune reactions.