176Lu Cavitating Squamous Cell Carcinoma

CXR Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Frontal CXR shows a cavitating mass in the superior segment of the right lower lobe
Ashley Davidoff MD TheCommonVein.net 176Lu 136731
CXR Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Frontal and lateral CXR show a cavitating mass in the superior segment of the right lower lobe
Ashley Davidoff MD TheCommonVein.net 176Lu 136732
CT Emphysema
50 year old male with cough and weight loss
Axial CT through the upper lung fields, shows extensive paraseptal emphysema, more prominent in the right upper lobe associate with mild centrilobular emphysema
Ashley Davidoff MD TheCommonVein.net 176Lu 136735
CXR and CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Frontal and lateral CXR are correlated with corresponding coronal and sagittal CT reconstructions of the cavitating mass in the superior segment of the right lower lobe
Ashley Davidoff MD TheCommonVein.net 176Lu 136736
CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Coronal and sagittal CT reconstructions show a cavitating mass in the superior segment of the right lower lobe (upper images) correlated with axial images (lower panel)
Ashley Davidoff MD TheCommonVein.net 176Lu 136737
CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Axial CT reconstructions shows a cavitating mass in the superior segment of the right lower lobe
Ashley Davidoff MD TheCommonVein.net 176Lu 136734

 

 

 

CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
Coronal CT reconstructions shows a cavitating mass in the superior segment of the right lower lobe
Ashley Davidoff MD TheCommonVein.net 176Lu 136733

PET CT at the Time of Diagnosis

CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
CT in the axial plane (upper image) shows a cavitating mass in the superior segment of the right lower lobe correlated with the axial PET image which shows dominant medial hypermetabolic activity with necrosis of more than 50% of the tumor.
Ashley Davidoff MD TheCommonVein.net 176Lu 136738

PET CT Following 9 Months of Chemo-Radiation Treatment

CT Cavitating Squamous Cell Carcinoma 9 Months Following Chemoradiation Therapy
50 year old male with cough and weight loss
CT in the axial plane (upper image) shows resolution of the cavitating mass in the superior segment of the right lower lobe confirmed by the axial PET image. Post XRT fibrosis is noted in the apical segment of the RLL
Ashley Davidoff MD TheCommonVein.net 176Lu 136739

3 Years Later
PET Negative Thickening of the Broncho-Vascular Bundle

CT Cavitating Squamous Cell Carcinoma 3 years After Chemoradiation Therapy
50 year old male with cough and weight loss
CT in the axial plane shows resolution of the cavitating mass in the superior segment of the right lower lobe confirmed by the axial PET image. However there is progressive thickening of the bronchovascular bundle and close follow up would be needed. Post
XRT fibrosis is noted in the apical segment of the RLL
Ashley Davidoff MD TheCommonVein.net 176Lu 136741

4 Years Post Initial Diagnosis
Broncho-Vascular Bundle Progressive Thickening
Post XRT Changes

CT Cavitating Squamous Cell Carcinoma 4 years After Chemoradiation Therapy
CT in the axial plane shows resolution of the cavitating mass in the superior segment of the right lower lobe confirmed by the axial PET image.
However there is progressive thickening of the bronchovascular bundle and PET scan would be indicated.
Post XRT fibrosis is progressive in the apical segment of the RLL.
There is background extensive paraseptal and centrilobular emphysema.
Ashley Davidoff MD TheCommonVein.net 176Lu 136742

Overview of a Cavitating Squamous Carcinoma Over 4 years

Overview of a Cavitating Squamous Carcinoma Over 4 years
a) Cavitating mass at presentation 4 years prior
b) 9 months following chemoradiation shows complete resolution of the mass which was conformed by PET CT with post XRT radiation fibrosis
c) 3 years prior – Persistent fibrotic changes without recurrence
d) 1 year ago – PET negative thickening of the RLL bronchovascular bundle with progressive fibrosis
e) Current Ongoing thickening of the RLL bronchovascular bundle with progressive fibrosis and new pleural effusion Await PET
Ashley Davidoff MD TheCommonVein.net 176Lu
CT Cavitating Squamous Cell Carcinoma
50 year old male with cough and weight loss
CT in the axial plane (upper image) shows a cavitating mass in the superior segment of the right lower lobe correlated with the axial PET image which shows dominant medial hypermetabolic activity with necrosis of more than 50% of the tumor.
Ashley Davidoff MD TheCommonVein.net 176Lu 136738
CT Cavitating Squamous Cell Carcinoma 9 Months Following Chemoradiation Therapy
50 year old male with cough and weight loss
CT in the axial plane (upper image) shows resolution of the cavitating mass in the superior segment of the right lower lobe confirmed by the axial PET image. Post XRT fibrosis is noted in the apical segment of the RLL
Ashley Davidoff MD TheCommonVein.net 176Lu 136739
CT Cavitating Squamous Cell Carcinoma 1 year After Chemoradiation Therapy
50 year old male with cough and weight loss
CT in the axial plane shows resolution of the cavitating mass in the superior segment of the right lower lobe confirmed by the axial PET image.
Post XRT fibrosis is noted in the apical segment of the RLL
Ashley Davidoff MD TheCommonVein.net 176Lu 136740