Nodules – Fissural sarcoidosis (classic association) amyloidosis – nodular form lymphocytic interstitial pneumonia (LIP) lymphangitic carcinomatosis: silicosis coal worker’s pneumoconiosis: Sarcoidosis 42 year old male with a history of sarcoidosis.The axial CTscan shows thickening and irregularity of the major fissure, a band of fibrosis in the right upper lobe, thickening of a segmental bronchus in the right upper lobe and bronchocentric fibrosis in the left upper lobe and multiple micronodulesAshley Davidoff MD TheCommonvein.net lungs sarcoid 002 Bilateral fissural thickening CT 2 months laterCourtesy Paul Kohanteb MDTheCommonVein.net Patient with sarcoidosis showing nodules along the chains of lymphatic distribution including the pleura, and fissureskeywords lung pleura fissures and around the bronchikey words lymphatics interstitium interstitial disease fx nodules dx sarcoidosis CTscan 446843Ashley Davidoff MD TheCommonVein.net FISSURAL BASED NODULES51-year-old male with history of sarcoidosisFissural based nodules Subpleural nodules Micronodules along the lymphovascular andbronchovascular bundles of the secondary lobuleCalcified nodule some of which are surrounded by soft tissue of the granulomaAshley Davidoff MD TheCommonVein.net Amyloidosis Fissural Based Amyloid Nodule with Central CalcificationAxial CT images through the right upper lobe shows a solid amyloid nodule with central calcification abutting the major fissure. These features, although not pathognomonic are characteristic. Sarcoidosis would be a radiological consideration as wellAshley Davidoff Boston Medical Center TheCommonvein.net LV-006 Fissural Based Amyloid Nodule and Centrilobular NodulesAxial CT images through the chest shows a Fissural based amyloid nodule along the left major fissure (a,b) Images c and d show posterior peripheral centrilobular nodules. In image c the nodules are associated with mosaic attenuation. The ground glass nodule in d could reflect alveolar septal disease withground glass changes surrounding a centrilobular noduleAshley Davidoff Boston Medical Center TheCommonvein.net LV-014c TB Coronal CTscan Shows Calcified Granulomata on the Fissure in the Anterior Segment of the Left Lower LobeCT scan of TB with Calcified Graulomata Centered around Major fissure and Bronchioles with Atelectasis and BronchiolectasisAshley Davidoff MD The CommonVein.net granulomata-along-fissures-010 Axial CTscan Shows Small Airway Associated with a Calcified Granuloma and Granulomas along the Major Fissure in the Anterior Segment of the Left Lower Lobe with Bronchiole Wall ThickeningCT scan of TB with Calcified Granulomata Centered around Major fissure and Bronchioles with Atelectasis and BronchiolectasisAshley Davidoff MD The CommonVein.net granulomata-along-fissures-006 Axial CTscan Shows Small Airway Associated with a Calcified Granuloma in the Anterior Segment of the Left Lower Lobe with Bronchiole Wall ThickeningCT scan of TB with Calcified Graulomata Centered around Major fissure and Bronchioles with Atelectasis and BronchiolectasisAshley Davidoff MD The CommonVein.net granulomata-along-fissures-007