Cancer Imaging Introduction

Introduction Imaging is essential to the diagnosis and staging of lung cancer and  therefore intimately related to the treatment.  The advances made in imaging over the last two decades have radically changed the diagnostic approach to cancer.  Although chest X-ray is an important study, in the face of the new technology it lags significantly in … Continue reading Cancer Imaging Introduction

000 Small Cell Carcinoma

Introduction Small Cell Carcinoma Small cell lung cancers (aka SCLC and oat cell cancer) is a malignant condition of the epithelium usually arising from the central airways and specifically arising from the eneterochromaffin or Kulchitsky cell which embryologically originates from the neural crest.  They account for 15-25% of lung cancers, and thus are less common … Continue reading 000 Small Cell Carcinoma

Cancer Pathology

Classification of Diseases In this section we discuss the various ways lung cancer has been classified. The two most important classifications are the histological and the TNM staging classifications. The histopathological classifications divide the disease into two fundamental groups as we discussed in above in the sttrucural principles section; small cell and non small cell … Continue reading Cancer Pathology

Faces of Cancer

SVC Syndrome 76-year-old female with central lung cancer and superior vena cava (SVC) syndrome as noted by this scout film following contrast injection, where contrast is trapped in the right subclavian system because of the obstruction of inflow. Note also the significant swelling of the face and neck which was new for this patient. Ashley … Continue reading Faces of Cancer

Cancer Result

Introduction The result is space occupying disease and depending on the location and degree of structural change symptomatology clinical and radiological findings will differ. Partial obstruction may cause focal emphysema while a total obstruction may lead to segmental or subsegmental atelectasis. Secondary infection may result in bronchitic, pneumonic change and even abscess formation Venous structures … Continue reading Cancer Result

Cancer Pathogenesis

Introduction In this section we deal with the back and forth battle of the malignant process with the bodies defence mechanism with the structural and functional result that follows. Initiating Event The initiating event is presumably the effect of a carcinogen on the genetic makeup of a cell or group of cells that survive the … Continue reading Cancer Pathogenesis